Montelukast Sodium

•Montelukast sodium is an oral, potent, and selective antagonist at CysLT Rs. which mediates the bronchoconstrictor and proinflammatory actions of the CysLTs in asthma and Asthma Rhinitis.

 – Both as monotherapy or in combination with inhaled corticosteroids, montelukast produced clinically relevant improvements in asthma-related parameters, including symptoms, lung function parameters, quality of life, and the number of asthma exacerbations.

Fexofenadine Hydrochloride

– Fexofenadine hydrochloride (HCI) is a second-generation, selective histamine Hi-receptor antagonist, approved to relieve SAR symptoms in adults and children.

Fexofenadine, the active metabolite of terfenadine, is a selective histamine Hi receptor antagonist that displays some anti-inflammatory properties. 

Acebrophylline

•Acebrophylline is an airway mucus regulator with anti-inflammatory action that reduces the hyper-responsive, inflammatory condition more markedly and more promptly than ambroxol.

•Therapeutically effective in reducing the frequency of episodes of bronchial obstruction and reducing the need for $2-agonists, and improving indexes of ventilatory function.