Ceftibid-200 DT for Infections

🔬 Introduction

Ceftibid-200 DT Tablet, manufactured by Minova Life Sciences, is a dispersible antibiotic formulation containing Cefixime Trihydrate IP 200mg. As a broad-spectrum third-generation cephalosporin, it provides targeted action against various bacterial infections, especially of the respiratory and urinary tract.

⚕️ Pharmacokinetics & Bioavailability

Cefixime exhibits high oral absorption, with bioavailability ranging between 40–50%, which improves when taken with food. The drug is highly protein-bound (~65%) and has a plasma half-life of 3–4 hours, allowing once or twice daily dosing.

🦠 Indications & Uses

• Upper respiratory tract infections (pharyngitis, tonsillitis)

• Lower respiratory tract infections (bronchitis, mild pneumonia)

• Urinary tract infections

• Gonorrhea (uncomplicated)

• Otitis media (ear infections)

💊 Dosage & Administration

• Adults & children ≥12 years: One tablet (200mg) once or twice daily, as per physician’s direction.

• Take after food for better absorption.

📌 Administration Guidelines

• Disperse the tablet in a teaspoon of water before swallowing.

• Do not crush or chew.

• Complete the prescribed course even if symptoms improve.

⚙️ Mechanism of Action

Cefixime inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), resulting in cell lysis and death. It’s effective against gram-positive and gram-negative organisms.

🔬 Effective Against

• Streptococcus pneumoniae

• Haemophilus influenzae

• Escherichia coli

• Proteus mirabilis

• Neisseria gonorrhoeae

⚠️ Warnings & Precautions

• Avoid in known allergy to cephalosporins or penicillins.

• Use with caution in renal impairment.

• Not recommended for infants below 6 months.

• Monitor for diarrhea, which may indicate pseudomembranous colitis.

🚨 Adverse Effects

• Nausea, vomiting, and abdominal pain

• Headache

• Diarrhea

• Skin rash or allergic reaction (rare)

• Elevated liver enzymes (occasional)

⚡ Drug Interactions

• May reduce efficacy of oral contraceptives

• Increased risk of nephrotoxicity with aminoglycosides

• Can interact with anticoagulants (monitor INR)

📦 Storage Conditions

• Store in a cool, dry place below 25°C

• Protect from moisture and direct sunlight

• Keep out of reach of children

🔗 Explore More from the Ceftibid Range

Discover other strengths and formulations of Cefixime:

• Ceftibid-100 DT Tablet – Cefixime Trihydrate IP 100mg (Dispersible)

• Ceftibid-100 Dry Syrup – Cefixime Anhydrous IP 100mg

• Cefibid OF Dry Syrup – Cefixime 50mg + Ofloxacin 50mg

• Cefibid-50 Dry Syrup – Cefixime Anhydrous IP 50mg

Click above to read full product blogs.

🏆 Conclusion

Ceftibid-200 DT Tablet is a trusted and clinically effective choice for treating a wide range of bacterial infections, especially in patients preferring a dispersible dosage form. Backed by Minova Life Sciences’ commitment to quality and safety, it remains a physician-recommended product.

📞 Get in Touch

📱 Phone: +91-9845329972
📧 Email: info@minovalifesciences.com
🌐 Website: www.minovalifesciences.com