Sitagliptin Phosphate
- Sitagliptin is the first antidiabetic agent from the class of dipeptidyl peptidase-4 enzyme 1
- Approved by the US Food and Drug Administration (FDA) for use with diet and exercise to improve glycemic control in adult patients with type 2 diabetes. 1
- Sitagliptin monotherapy improved indices of glycemic control compared to placebo and was generally well-tolerated in patients with type 2 diabetes.2
- It not only improves blood glucose control but also body weight, blood pressure and lipid profile in type 2 diabetic hyperlipidaemia patients.3
- Reduced postprandial plasma levels of TG-rich lipoproteins of both intestinal and hepatic origin.4
- Works by increasing incretin hormone levels, reducing circulating plasma FFA concentrations and improving insulin sensitivity and β-cell function.4